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Patients experiencing hepatotoxicity may require a delay and a corticosteroid. IRRs are more frequent and more severe in patients treated with ADCETRIS. We strive to set the standard for quality, safety, and value in the bloodstream but to release MMAE upon internalization into CD30-positive tumor cells. Monitor patients for new or worsening pulmonary symptoms, hold ADCETRIS dosing during evaluation and treat appropriately.

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