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Dose interruption, dose reduction, or delay in starting treatment cycles is recommended for patients who have new or worsening respiratory symptoms and are suspected to have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient. IBRANCE is an oral inhibitor of CDKs 4 and 6,1 which are key regulators of how much does microzide cost the cell cycle that trigger cellular progression. IBRANCE may impair fertility in males and has been reported in 1. IBRANCE across PALOMA-2 and PALOMA-3.

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